Congenital hypothyroidism missed on screening.

Congenital hypothyroidism missed on screening.

Three patients with congenital hypothyroidism missed on routine screening due to normal low thyrotrophin concentrations in the neonatal period presented in later childhood. Clinicians should remain aware of hypothyroidism as a cause of morbidity in early childhood despite a national screening programme.

The Importance of Screening in Congenital Hypothyroidism

Introduction: Congenital hypothyroidism is the most common cause of preventable mental retardation in children. However, early diagnosis and treatment improve the prognosis of mental retardation. Clinical diagnosis of Congenital hypothyroidism is not also evident in the neonatal period. Therefore, screening all newborns for early diagnosis and treatment is essential. This paper aimed to analyze...

Screening for congenital hypothyroidism.

OBJECTIVE To review the screening program for congenital hypothyroidism in the Riyadh Al-Kharj Hospital Programme, Riyadh, Kingdom of Saudi Arabia, and to investigate the clinical and biochemical characteristics of affected infants. METHODS The study was carried out from 1985 to 2000 in the Clinical Chemistry Division, Department of Pathology, Riyadh Armed Forces Hospital, Kingdom of Saudi Ar...

Screening for congenital hypothyroidism.

The development of efficient micromethod assay systems for thyroid hormones and thyroid-stimulating hormone makes possible detection of this condition in the neonate, when clinical signs seldom arouse suspicion. Starting treatment by age three months has been shown to prevent severe intellectual deficit; thus mass screening can be considered cost-effective as compared with outlays for special c...

Screening for congenital hypothyroidism.